Systems Matter Seminar | Materials-Driven Strategies for Translational Bioelectrical Interfaces
he Systems Matter Seminar Series brings experts in the areas of materials, devices, and processes together once a month to share innovative research in those areas. The seminar series meets during the academic year at noon in the Marcus Nanotechnology Building conference rooms (1116-1118).
If you would like to be added to the mailing list and receive information related to the Systems Matter Seminars and other events, please sign up for our newsletter.
Abstract: The field of electronic and photonic biointerfaces is advancing rapidly, propelled by breakthroughs in materials science, biophysics, and physical chemistry. This interdisciplinary convergence has led to the design of bioelectronic systems with unprecedented multifunctionality, including the integration of living components. These systems are poised to revolutionize sensing, biological modulation, and regenerative medicine by addressing challenges at the interface of synthetic and biological materials. Our research focuses on the development of non-genetic bioelectronic platforms that exploit advanced materials design to achieve precise and scalable biological interactions across molecular, cellular, and tissue levels. Key achievements include the creation of optoelectronic systems for photostimulation based on nanoporous and non-porous heterojunctions. These materials provide enhanced control over charge transport and light-matter interactions, enabling highly targeted therapeutic interventions. Another significant focus is the seamless integration of living cells with hydrogels and wearable bioelectronics. By investigating dynamic material-biology interface formation and the principles of bioelectrical signaling, we have developed platforms that mimic and enhance natural biological processes. Future directions in our work aim to extend the capabilities of bioelectronic systems through the discovery of novel materials and interface designs. By bridging the gap between synthetic constructs and living systems, we seek to establish new paradigms in bioelectronic modulation and sensing, ultimately translating these innovations into clinical applications that advance human health and well-being.
Bio: Dr. Bozhi Tian earned his Ph.D. in Physical Chemistry from Harvard University and completed postdoctoral research in regenerative medicine at the Massachusetts Institute of Technology. At the University of Chicago, his research focuses on developing new materials for bioelectronics, employing semiconductor- and electronics-based tools to investigate (sub-)cellular dynamics and soft-hard interface interactions, and the translational applications of diverse bioelectrical systems. Dr. Tian’s work has been recognized with several honors, including the Raymond and Beverly Sackler International Prize in the Physical Sciences, the Presidential Early Career Award for Scientists and Engineers (PECASE), recognition as an MIT Technology Review Innovator Under 35 (TR35) in 2012, and the 2023 Faculty Award for Excellence in Graduate Teaching and Mentoring from the University of Chicago.